HP1 shares an ~50-amino acid NH 2 -terminal sequence motif, the chromo domain, with polycomb, an important regulatory gene that functions in the stable repression of homeotic genes during Drosophila development (28 ).

To determine whether the conserved domains, the chromo, SET, and cysteine-rich regions, were also critical for Clr4 HMTase activity, we tested mutant Clr4 proteins for HMTase activity.

All Nature is smiling, in fact, with one large, comprehensive smile, exactly like a first-class PRANG chromo with a fresh coat of varnish upon it.

It was manifest that we all felt that we ought to send the poor shoemaker SOMETHING. There was long and thoughtful discussion of this point; and we finally decided to send him a chromo.

The neglected warehouse turned out to be a treasury of calendar art from the 1930s through the 1970s, years when chromo art calendars were a major advertising medium, a vehicle for national pride, and a fixture in nearly every home, business, and school.

That dried-up lady snob lived behind lace curtains all her life. She's of no more importance than a chromo.

Chromo

Meaning

Noun

Adj

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