Polyclonal antibodies were prepared against the period gene product, which influences biological rhythms in D. melanogaster, by using small synthetic peptides from the per sequence as immunogens.

Certain gene functions, however, are inherently dosage-sensitive (Fisher and Scambler, 1994). These include:
gene products that are part of a quantitative signaling system whose function depends on partial or variable occupancy of a receptor, DNA-binding site, etc.;
gene products that compete with each other to determine a developmental or metabolic switch;
gene products that co-operate with each other in interactions with fixed stoichiometry (such as the α and β globins or many structural proteins).
In each case the gene product is titrated against something else in the cell.

In this case, we find that the majority of the predicted protein matches the FMR1 gene product but that we have introduced some novel peptide sequence at the amino-terminal end as well as some near the carboxy terminus.

Gene product

Meaning

Noun