The least admixture of a lie, -- for example, the taint of vanity, the least attempt to make a good impression, a favorable appearance, -- will instantly vitiate the effect.

‘Mr Rose,’ says the Physician, ‘this man was brought to us from Russia. Precisely such a case of vitiated judgment as I describe at length in my Treatise on Madness. Mayhap you have read it?’

Unfortunately, as Anderson and Sørenson (1996) and Bowsher (2002) document, instrument proliferation can vitiate the test.

We have examined with care all known negative feedback mechanisms, such as increase in low or middle cloud amount, and have concluded that the oversimplifications and inaccuracies in the models are not likely to have vitiated the principal conclusions that there will be appreciable warming.

The robber does not intentionally vitiate people, but the governments, to accomplish their ends, vitiate whole generations from childhood to manhood with false religions and patriotic instruction.

‘Crush the cockatrice,’ he groaned, from his death-cell. ‘I am dead in law’ – but of the girl he denied that he had ‘attempted to vitiate her at Nine years old’; for ‘upon the word of a dying man, both her Eyes did see, and her Hands did act in all that was done’.

[…]all the hinges of the animal frame are subverted, every animal function is vitiated; the carcass retains but just life enough to make it capable of suffering.

After the trials, Turkey's secular elite was completely vitiated.

Vitiate

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